11 Antiphospholipid Antibodies
Description
This article is from the Miscarriage FAQ, by Laura Brooks brook006@mc.duke.edu with numerous contributions by others.
11 Antiphospholipid Antibodies
There are consequences for every action. Pregnancy is no different. Each
time a pregnancy doesn't make it inside your body, there are conseguences.
This includes even the act of fertilizing an egg. A 20% chance exists with
each pregnancy and/or pregnancy loss that one problem make create another.
In all probability, this is why we now have the antiphospholipid antibody
problem. The phospholipids are a sort of glue necessary in every pregnancy.
They look like little snowfalkes (of fat) which have a sticky end to hold
the cells together. They fuse into other cells and act like a membrane .
Think of them like a swimming pool filter. The phospholipids filter the
nourishment from your blood and than in turn filter the baby's waste back
through the placenta which feeds the baby and produces the BHCG throughout
pregnancy.
Phosphlioids necessary in pregnancy are: cardiolipin, ethanolamine,
phosphatidic acid, glycerol and serine . In our particular case I have
developed an immunity to ethanolamine (this is the "glue" which also sticks
the sperm to the egg). Just like being immune to chicken pox and measles (I
no longer get them) I now am immune ethanolamine so I no longer get
pregnant. Ethanolamine and serine are also the "glues" which are necessary
to build the placenta, so even if I were to get pregnant I still wouldn't
be capable of building the placenta. Couples with this problem are good
candidates for multiple failures at IVF / GIFT / ZIFT cycles. Once you have
developed an immunity to one of the phospholipids there will be an attack
on the baby even in a donor cycle! This problem is 97% efficient in the end
to a pregnancy.
However the key which locks this glue in place is your own body's natural
heparin. Most people think of heparin as a blood thinner but in the case of
combating the phospholipids, heparin acts in a way to lock the glue in
place and keep the organs attached. The heparin must be taken preconception
because the cells are already functioning as they are lining up around the
egg. If there is a pregnancy 86% of the woman will become mothers. If they
wait until after a postive pregnancy test 75% will lose their babies again.
After the immunizations, treatment with heparin and baby asprin
preconception 30% of Dr. Beer's patients have been successful without the
use of ART.
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