This article is from the Static Electromagnetic Fields and Cancer FAQ, by John Moulder jmoulder@its.mcw.edu and the Medical College of Wisconsin with numerous contributions by others.
21) VV Shevchenko et al: [On the problem of induction of chromosome
aberrations in plants by a constant magnetic field], Genetika 14:1101-
1103 (1978).
Plant seeds were germinated in a static magnetic field at 900 mT and
1200 mT for 2 days, or dry seeds were exposed for 2 months to a 900 mT
static magnetic field. No increase in chromosome aberrations was
observed.
22) S Wolff et al: Magnetic resonance imaging: Absence of in vitro
cytogenetic damage, Radiology 155:163-165 (1985).
Human (stimulated and unstimulated) lymphocytes and CHO cells were
exposed for 12.5 hrs to a MRI unit with a static field of 2400 mT plus
100-MHz RF. No increases in chromosome aberrations or sister chromatid
exchanges were observed.
23) S Wolff et al: Tests for DNA and chromosomal damage induced by
nuclear magnetic resonance imaging, Radiology 136:707-710 (1980).
CHO cells were exposed for 14 hrs to a 350 mT static field together
with a gradient field (up to 0.2 mT/cm), and the RF fields (15 MHz at 5
mW/cm2) that would be used in MRI. Experiments were also run with
higher RF power. No chromosomal aberrations were observed.
24) E Yamazaki et al: Effect of Gd-DTPA and/or magnetic field and
radiofrequency exposure on sister chromatid exchange in human peripheral
lymphocytes, Acta Radiol. 34:607-611 (1993).
PHA-stimulated lymphocytes were exposed to a 1500 mT static field plus
RF at 64 MHz (SAR of 0.4 W/kg) and Gd-DTPA. The addition of the Gd-DTPA
caused an increase in chromosome aberrations, but no effects on
chromosome aberrations were observed for the fields alone.
25) ME Frazier et al: In vitro evaluations of static magnetic fields,
In: "Biological effects of extremely low frequency electromagnetic
fields", RD Phillips MF Gillis WT Kaune et al., eds., Technical
Information Center, US Department of Energy, Springfield, pp. 417-435
(1979).
Mammalian cells were exposed to 500 or 1000 mT static fields for 2, 4
or 24 hours, or to 100 or 300 mT fields for up to 67 days. No effects
on cell growth rates, cell viability or cell transformation were
observed.
26) RL Moore: Biological effects of magnetic fields: studies with
microorganisms, Can. J. Microbiol. 25:1145-1151 (1979).
Ames test with exposures at 0 to 0.3 Hz to fields of 15 and 30 mT. No
increase in mutations were observed.
27) JL Schwartz & LE Crooks: NMR imaging produces no observable
mutations or cytotoxicity in mammalian cells, Amer. J. Roent. 139:583-
585 (1982).
Mammalian cells were exposed for 24 hrs to a static field at 300 mT,
together with a gradient field (up to 0.2 mT/cm), and the RF fields (15
MHz at 3 mW/sq.-cm) that would be used in MRI. No cytotoxicity or
mutagenicity (6-TG system) were observed.
28) A Thomas & PG Morris: The effects of NMR exposure on living
organisms. I. A microbial assay, Br. J. Radiol. 54:615-621 (1981).
Bacteria were exposed to a 1000 mT static field and to the conditions
used in an MRI (900 mT static field plus RF and gradient field). Not
mutagenic or cytotoxic effects were observed.
29) J McCann, F Dietrich, C Rafferty, et al: A critical review of the
genotoxic potential of electric and magnetic fields, Mutat. Res. 297:61-
95 (1993).
"The preponderance of evidence suggests that neither ELF nor static
electric and magnetic fields have a clearly demonstrated potential to
cause genotoxic effects."
30) PG Kale & JW Baum: Genetic effects of strong magnetic fields in
Drosophila melanogaster, II. Lack of interaction between homogeneous
fields and fission neutron-plus-gamma radiation, Environ. Mutagen.
2:179-186 (1980).
No enhancement of radiation-induced mutations in fruit flies exposed
to a 3700 mT static field.
 
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