Any Other Research Extracts On This Subject?
Description
This article is from the Dental Amalgam FAQ, by anonymous.
Any Other Research Extracts On This Subject?
Plenty. Here are a few interesting ones..
Nylander M, Friberg L, Lind B: Mercury concentrations in the human
brain and kidneys in relation to exposure from dental amalgam fillings.
Swedish Dental Journal 1987; 11: 179-87.
ABSTRACT: Samples from the central nervous system (occipital lobe cortex,
cerebellar cortex and ganglia semilunare) and kidney cortex were
collected from autopsies and analysed for total mercury content
using neutron activation analyses. Results from 34 individuals
showed a statistically significant regression between the number
of tooth surfaces containing amalgam and concentration of mercury
in the occipital lobe cortex (mean 10.9, range 2.4-28.7 ng Hg/g
wet weight). The regression equation y = 7.2 + 0.24x has a 95%
confidence interval for the regression coefficient of 0.11-0.37.
In 9 cases with suspected alcohol abuse mercury levels in the
occipital lobe were, in most cases, somewhat lower than expected based
on the regression line. The observations may be explained by an inhibition
of oxidation of mercury vapour. The regression between amalgams and
mercury levels remained after exclusion of these cases. The kidney
cortex from 7 amalgam carriers (mean 433, range 48-810 ng Hg/g wet
weight) showed on average a significantly higher mercury level
than those of 5 amalgam-free individuals (mean 49, range 21-105
ng Hg/g wet weight). In 6 cases analysis of both inorganic and
total mercury was carried out. A high proportion (mean 77% SD
17%) of inorganic mercury was found. It is concluded that the
cause of the association between amalgam load and accumulation
of mercury in tissues is the release of mercury vapour from
amalgam fillings.
Sallsten G, Thoren J, Barregaard L & Schuetz A. (Och Skarping G??) Long-term Use of
Nicotine Chewing Gum and Mercury Exposure from Dental Amalgam Fillings. J Dent Res
75(1):594-598 (1996)
ABSTRACT: "In experimental studies, chewing gum has been shown to increase the release rate of
mercury vapor from dental amalgam fillings. The aim of the present study was to investigate the
influence of long-term frequent chewing on mercury levels in plasma and urine. Mercury levels in
plasma (P-Hg) and urine (U-Hg), and urinary cotinine were examined in 18 subjects who regularly
used nicotine chewing gum, and in 19 referents. Age and number of amalgam surfaces were similar
in the two groups. Total mercury concentrations in plasma and urine were determined by means of
cold vapor atomic absorption spectrometry. Urinary cotinine was determined by gas
chromatography-mass spectrometry. The chewers had been using 10 (median) pieces of gum per
day for the past 27 (median) months. P-Hg and U-Hg levels were significantly higher in the chewers
(27 nmol/L and 6.5 nmol/mmol creatinine) than in the referents (4.9 nmol/L and 1.2 nmol/mmol
creatinine). In both groups, significant correlations were found between P-Hg or U-Hg on the one
hand and the number of amalgam surfaces on the other. in the chewers, no correlations were found
between P-Hg or U-Hg and chewing time per day or cotinine in urine. Cotinine in urine increased
with the number of pieces of chewing gum used. The impact of excessive chewing on mercury levels
was considerable."
Osterblad M, Leistevuo J, Leistevuo T, Jarvinen H, Pyy L, Tenovuo J & Huovinen P.
Antimicrobial and Mercury Resistance in Aerobic Gram-Negative Bacilli in Fecal Flora
among Persons with and without Dental Amalgam Fillings. Antimicrobial agents and
chemotherapy 39(11):2499 (1995)
ABSTRACT: "Antimicrobial resistance is more widespread than can be accounted for as being a
consequence of the selection pressure caused by the use of antibiotics alone. In this study, we tested
the hypothesis that a high mercury content in feces might select for mercury-resistant bacteria and
thus for antimicrobial resistance linked to mercury resistance. Three subject groups with different
exposures to dental amalgam fillings were compared. None of the subjects had taken antimicrobial
agents during the three preceding months or longer. The group exposed to dental amalgam (n = 92)
had 13 times more mercury in feces than the group that had never been exposed to amalgam (n =
43) and the group whose amalgam fillings had been removed (n = 56). No significant differences in
either mercury resistance or antibiotic resistance in the fecal aerobic gram-negative flora of these
subject groups were seen. The following antimicrobial resistance frequencies were detected with a
replica plating method: > or = 1% resistance was seen in 40% of the subjects for ampicillin, 14% of
the subjects for cefuroxime, 6% of the subjects for nalidixic acid, 14% of the subjects for
trimethoprim, 19% of the subjects for sulfamethoxazole, and 25% of the subjects for tetracycline.
The amount of mercury in feces derived from amalgam was not selective for any resistance factors
in aerobic gram-negative bacteria, but antimicrobial resistance was widespread even among healthy
subjects with no recent exposure to antibiotics."
Lindqvist B & Mornstad H. Effects of removing amalgam fillings from patients with
diseases affecting the immune system. Med Sci Res 24(5):355-356 (1966)
ABSTRACT: "53 patients with complaints which they attributed to their amalgam fillings, and with
pathological tests indicating abnormality of the immune system, were followed for 1-3 years after the
removal of all, part of, or none of their amalgam fillings. Within the group of 34 individuals who had
all their amalgam fillings replaced, there was a significant number of decreased antibody titres, but
only two had normalised their laboratory tests after 1-3 years. A significant improvement in
subjective symptoms occurred in 20 (59%) of cases. In the group of patients who still had amalgam
fillings, there were no statistically significant changes in the antibody titres. It thus seems that mercury
released from amalgam fillings may initiate or support an ongoing immune disease. However. this
study group was rather heterogeneous, and had received various pharmacological treatments.
Further studies, are, therefore, needed to confirm, or refute, the results."
Title: A comparison of mental health of multiple sclerosis patients with silver/mercury dental fillings: and those with fillings removed.
Author: Siblerud RL
Address: Rocky Mountain Research Institute, Inc., Colorado.
Source: Psychol Rep, 70: 3 Pt 2, 1992 Jun, 1139-51
Abstract: In this study was compared the mental health status of 47 multiple sclerosis patients with silver/mercury tooth fillings (amalgams) to that of 50 patients with their fillings removed. On the Beck Depression Inventory the multiple sclerosis subjects with amalgams suffered significantly more depression while their scores on the State-Trait Anger Expression Inventory indicated the former group also exhibited significantly more anger. On the SCL-90 Revised, subjects with amalgam fillings had significantly more symptoms of depression, hostility, psychotism, and were more obsessive-compulsive than the patients with such fillings removed. On a questionnaire containing 18 mental health symptoms multiple sclerosis subjects with amalgam fillings reported a history of 43% more symptoms than those without amalgam fillings over the past 12 months. These data suggested that the poorer mental health status exhibited by multiple sclerosis subjects with dental amalgam fillings may be associated with mercury toxicity from the amalgam.
Title: Evidence that mercury from silver dental fillings may be an etiological factor in multiple: sclerosis.
Author: Siblerud RL; Kienholz E
Address: Rocky Mountain Research Institute, Inc., Fort Collins, CO 80524.
Source: Sci Total Environ, 142: 3, 1994 Mar 15, 191-205
Abstract: This paper investigates the hypothesis that mercury from silver dental fillings (amalgam) may be related to multiple sclerosis (MS). It compares blood findings between MS subjects who had their amalgams removed to MS subjects with amalgams. MS subjects with amalgams were found to have significantly lower levels of red blood cells, hemoglobin and hematocrit compared to MS subjects with amalgam removal. Thyroxine levels were also significantly lower in the MS amalgam group and they had significantly lower levels of total T Lymphocytes and T-8 (CD8) suppressor cells. The MS amalgam group had significantly higher blood urea nitrogen and lower serum IgG. Hair mercury was significantly higher in the MS subjects compared to the non-MS control group. A health questionnaire found that MS subjects with amalgams had significantly more (33.7%) exacerbations during the past 12 months compared to the MS volunteers with amalgam removal. The paper also examines epidemiological correlations between dental caries and MS; as well as how mercury could be causing the pathological and physiological changes found in multiple sclerosis.
Also make sure to read these books: Poison in Your Teeth: Mercury Amalgam (Silver) Fillings...Hazardous to Your Health! and Mercury Detoxification by Tom McGuire
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