This article is from the Health Articles series.
Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs)
One of the newest classes of antidepressants, Serotonin/Norepinephrine Reuptake Inhibitors (SNRIs) act on both serotonin and norepinephrine, two neurotransmitters in the brain. They also have some effect on dopamine, another neurotransmitter. It is believed that SNRIs control depression by increasing the amounts of serotonin and norepinephrine in the brain. Venlafaxine, the only available SNRI, is a clean drug, which means it doesn't interact with other medications and has relatively few side effects.
Venlafaxine has side effects similar to the SSRIs. These include:
Most people experience few, if any, side effects while taking venlafaxine. If side effects are encountered, it's usually while the body is adjusting to the medication, and they soon disappear. It's possible, however, to experience side effects that aren't listed above.
If you experience any side effects, tell your health-care professional. If necessary, health-care professional can change the dose of your medication or switch you to an alternative medication.
Venlafaxine (an SNRI) can be dangerous if too much is taken. Be sure to follow your health-care professional's instructions carefully.
When first starting this medication, it's a good idea to be careful driving or operating machinery, just in case it makes you sleepy or dizzy.
You don't need to follow a special diet while taking an SNRI or have the level of medication in your blood checked.Check with your health-care professional before drinking any alcohol, but it's probably okay in very small amounts.
It's also important to check with your health-care professional before taking any other medications. Venlafaxine (an SNRI) doesn't interact with most other medications often, but it should never be taken MOAIs.. level.
 
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